Mersa was found unresponsive, slumped over the steering wheel of his car in Florida on 27 December.
Media reports indicate the cause of death was asthma attack, although the results of an autopsy have not yet been made public.
He was 31 and is survived by his wife and daughter.
Jo Mersa Marley, grandson of reggae legend Bob Marley has died at 31 years old. RIP
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— Daily Loud (@DailyLoud) December 28, 2022
Absolutely shocked to the core
What a delightful young man, we spent some time on tour in America a few times in recent years a real Marley to the core.
Wicked Sound, Beautiful Soul
Rest In Paradise Jo Mersa Marley
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— ALI CAMPBELL (@UB40) December 28, 2022
for one of the DJs on #RCNYE to have a special 10 to 20 minute tribute to Jo Mersa Marley on their set
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— THE Blaze (@blazey_blaze) December 29, 2022