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Study raises concerns over kidney injury risks linked to COVID-19 and other Vaccines

A study led by Dr. Hyeon Seok Hwang from Kyung Hee University Medical Center in South Korea, published in Scientific Reports has identified a significant increase in reported cases of vaccine-associated kidney injuries.

Analysing over 120 million global adverse drug reaction reports from the WHO’s VigiBase, researchers found a disproportionate number of acute kidney injury (AKI), glomerulonephritis (GN), and tubulointerstitial nephritis (TIN) cases linked to COVID-19 mRNA vaccines.

The study suggests younger individuals, particularly adolescents aged 12–17, may face higher risks, raising concerns over vaccine safety monitoring.

While the findings highlight statistical associations rather than causation, researchers call for further investigation into potential immunological and genetic predispositions, pre-vaccination kidney screenings for high-risk individuals, and long-term safety surveillance.

Despite limitations such as reporting bias, the study underscores the need for continued pharmacovigilance and transparent public health discussions on vaccine-related risks.

South Korean study news
Temporal changes in the reported counts of vaccine- and drug-associated renal adverse events, and a world map showing reported cases across continents. The reported counts of AKI (A), GN (B), and TIN (C) are presented over timeframe. The number of each renal AE for vaccines (red bars) and all drugs (blue bars) is listed, and the proportions of renal AEs among all drug-related AEs are displayed as percentages adjacent to the red bars. Globally reported counts of AKI (D), GN (E), and TIN (F) are shown across continents. Regions with higher counts are indicated in red, while those with lower counts are marked in blue. AKI, acute kidney injury; GN, glomerulonephritis; TIN, tubulointerstitial nephritis. Image – Scientific Reports.

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