Ange Capuozzo’s stunning finish set Italy on course for a deserved 22-15 victory over Wales at Stadio Olimpico, extending the visitors’ record losing streak to 14 matches.
Despite a late rally that included a penalty try and two yellow cards for Italy, Wales’ lack of discipline and 15 handling errors proved costly.
Tommaso Allan’s 17 points and Italy’s superior tactical execution ensured a first home win over Wales in 18 years.
The defeat drops Wales to a historic low of 12th in the world rankings, piling further pressure on head coach Warren Gatland.